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I approached my boss with some technical problem, expecting some answer. He barked, "GOO

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

GLE IT YOU MORON". I didnt got the answer still I asked shylessly, "Whats the meaning of

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

moron?". Again he screamed, "Google it you moron?". I returned to my desk and first goog

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ed the meaning of moron.. Idiot.

Somewhat frustrated I left office to watch a movie. Th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

first half was good, but there were surprises for me in the second half.

The hero was

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

sking heroine, "Darl, Do you love me?", A minute of silence and then the heroine replied

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

"Google it you moron". Because this new gen heroine writes a blog and she also posts ab

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

out her love afair.

I thought people have got answer for all questions, just say, "Goog

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e it you moron".

The angry young hero went to his home, and asked his mother, "Maa, saa

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

i duniya mujhe najayaz kahati hai, Batao kaun hai mera baap?". The modern maa with tears

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

in her eyes replied, "Google it you moron, you will definately get his name."

Now I sta

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ted to hate google, and left the movie hall. All time on my way to home I was thinking,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd wondering. Can't I ask simple questions to anyone now? Do I have to search go

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

gle for everything I want to know?

I was talking insanely with myself, I was n

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ear to my home, standing at crossroads I forgot which road goes to my home, I asked a ma

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

standing nearby, "Which road leads to Highway Signal?", The man replied, "Google it you

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

moron, you will get this information on website of Municipal Corporation."

Now I can't

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ear google's name anymore, I was screaming on the road, "Goooooogle eeeeeeeet uuuuuuuuuu

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

u moooorooooooooooooooooon"

You must be thinking Is this guy mad?, Well the answer is s

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

mple. "Google it you moron". You might find my name in on some mental hospital's website

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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