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Bigorexia?

Bigorexia?

I thought I’d heard it all. There’s anorexia, starving yourself to achieve thinness. And now there’s “bigorexia,” use of weight training and steroids to sa

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

tisfy the frantic compulsion to be bigger than anybody else.

Ana….mostly women get into.

Big-O (bigorexia) is mostly a “guy thing.”

Anorexia, bulimia and now, “bigorexia,” are

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

inked in that the people who do them, do them because they suffer from feelings of inferiority and inadequacy.

Did I say all Anas feel inferior? No. Did I say all Big-O’s feel in

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

erior? No.

Did I say losing weight is always bad? No. Or staying in shape is bad?

No!

Did I say working out in a gym is bad?

Did I? Did I?

A compulsion is a compulsion, just

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hat…not a physical disease. Many practioners of anorexia starve themselves to achieve the look of alleged perfection, that of a fashion model on TV. That’s okay, until you reach t

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e point you’re starving yourself to death.

With Big-O, you take the steroid and pump iron so you can feel superior to other people….because in reality you feel inferior to other

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

eople.

Barry Bonds is a little different.

He took steroids to achieve sports records and fame and money. Bonds cheated. His record is a fraud. He should have his number ripped o

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

f his back in front of the home town crowd, and his bat broken in front of him (in the Old West they used to break your sword, strip off your medals, and throw you out of the fort

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

.

Cheat! Cheat!

Where money and attention are involved, for those who crave them, the damage done from steroids to the liver, and bone marrow, is immaterial. So is the nasty lit

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

le side effect that steroid use shrinks your male organ. So, it doesn’t make everything bigger.

“Oh look at me. I’m ze big man! I take ze steroid and I can beat you up. So I’m ze

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

bigger man than you are.”

Technically called “muscle dysmorphia,” a Big-O-crazed guy will keep painfully pumping iron with an arm he recently broke in the gym. But ironically, st

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rangely, he also feels shy about his muscle mass, and tends to withhold sharing his body with others (embarrassed to show it).

He mainly looks at himself in the mirror…in privacy

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Thousands of men are reportedly afflicted, and some women.

There’s a whole subculture out there of Big-O.

If Bronze Age Greece was the age of heroes, then Big-O is the age of

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

heats and frauds. Posers.

I look at myself in the mirror for hours, lustfully, like you would at a beautiful woman. It’s all about me. Me. Aren’t I gorgeous? Look at my deltoids.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

A turn on. What lats. I’m beautiful. I owe it all to Big-O, and to steroids.

Now I’m going to move to another mirror and pose atop a velvet platform. I’ll blow myself a kiss. Ooo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

! I’m the only man in town. The only real man.

Three blocks away a female body builder who also pops steroids, has a real low voice, and hairier-than-normal underarms, and who no

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

secretly refers to herself as “Dominick,” is also posing in front of a mirror, saying the same thing.

“I will kiss my deltoid.”

Don’t worry, you Anas out there who want to achi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ve a false sense of security by feeling superior, striving for an imaginary level of perfection that can never be attained. Scientists will eventually invent a synthetic compound

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

hat can reduce you to the size of a tree branch.

And you Big-Os. Take heart. A growth hormone substance to ultimately be labeled “Colossus,” will in just ten years, allow you to

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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