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Studies have shown pregnancy stretch marks are a major cause of concern and anxiety for many pregnant women. And like mo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

st pregnant women, you have probably thought about the likelihood of getting stretch marks due to the changes you and you

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

body are experiencing through pregnancy.

Stretch marks occur when there is a rapid fluctuation in body size and during

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

regnancy, there is an increased chance of developing stretch marks as your body grows and then reduces in size after chil

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

birth.

The most common areas affected by pregnancy stretch marks are your stomach, thighs, buttocks, breasts and arms a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nd because stretch marks are small scars the best form of protection is prevention.

There are several ways of trying to

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

revent pregnancy stretch marks and some are more effective than others.

• Water

This may seem like common sense but you

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

will be surprised how many people only drink when there body is telling them that they are thirsty – this is too late. Y

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

u should keep your body hydrated and your skin elastic by drinking at least 6 – 8 cups of water every day.

• Nutrition

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

By eating sensibly and maintaining a balanced diet during pregnancy you will help feed the body and skin with essential v

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tamins and oil that help keep your skin healthy and elastic, helping to prevent pregnancy stretch marks.

• Pregnancy str

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tch mark prevention cream

The best form of preventing pregnancy stretch marks is to regularly apply 100% natural stretch

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

mark prevention cream to help regenerate and protect your skin and to strengthen the collagen and elastin found in the ep

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

idermis.

This regular stimulation will make your skin stronger, healthier and more elastic, ensuring it is better equipp

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d to deal with the stresses and pressures of your changing body shape.

By massaging these creams into your skin you bene

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

it in two ways. Firstly you can pamper yourself by slowly massaging your body, always a good thing while your body is ex

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

anding and aching. Second and most importantly, the skin is being massaged and this improves the circulation and revital

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ises your skin. The vitamins and natural herbs in the creams are being absorbed into your skin increasing your protection

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

against pregnancy stretch marks.

In conclusion, pregnancy stretch marks are a great concern for many women, how much is

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

p to you! By following the general tips above you can give your body the best chance of defeating pregnancy stretch marks

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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