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When it comes to moles tearing up your lawn it’s personal, isn’t it? Almost like they’re taunting you with their fresh runs ea

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ch morning. Daring you to stop them somehow. And it can be seriously disheartening when you can’t.

I mean think about it. T

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

here you are. You spend serious money to feed, water and care for your lawn. Not to mention what you shell out for a lawn ser

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ice to maintain your emerald oasis. And then BAM! Here come the moles to dig it all up in a tunneling frenzy. Criss-crossing

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

your pride and joy with the equivalent of ugly little mini dirt bike ruts. And let’s not even think about what those look lik

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

after a sudden summer downpour.

So it is any wonder the sight of such runs can cause some to consider explosives when looking

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

for a ways to go about eliminating ground moles? Please. Let’s hope it doesn’t come to that.

Of course with all that primpi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

g and pampering of your lawn, what you’ve basically done is create a mole vacation resort. Complete with neon welcome sign. A

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

nd to get rid of rid of the moles you’ve got to change that. At least a bit.

Basically, when it comes to eliminating ground m

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

les you’ve got two choices. Starve em out or drive em out.

How to Starve 'em Out
Moles thrive on a diet of grubs

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

and worms. Grubs are bad for your lawn. Worms are good. Sadly you can eliminate all traces of grubs and still have moles th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

riving on worms. Which says you can’t entirely starve them out since you want worms to aerate the soil. But getting rid of g

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ubs can make them work harder for their supper.

What you want to do as spring arrives is spread a quality grub control on your

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lawn. The idea is to kill the grubs to make your yard less like a mole fast food drive through. NOTE: In the past grub cont

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ol might have included milky spore. But not so much anymore since studies now show it’s ineffective.

How to Drive 'em Out<

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

/b>
Castor oil is a known mole repellent. The idea is to use one of the castor oil-based products on the market to conv

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nce them your neighbor’s lawn is a lot better place to dig. Just don’t expect miracles after one or even two applications.

Of

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

course while you may want instant results, patience is required. In fact it may take a couple of seasons to more or less mole

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

proof your lawn. But if you keep working at it by getting rid of their food source and making the place unattractive, the mole

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s will eventually move on to greener pastures. Thus eliminating ground moles and giving you back your perfectly manicured lawn

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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