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Relocation can be a stressful affair. Selling or renting your home, shipping belongings, saying bye to friends and family, leaving your

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

job and worrying about life and work in the new country are but a few of the pressures one feels before and during a relocation.

One ar

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ea of concern for parents is the children. Relocation with children doubles the stresses and worries. Most adults find relocation trauma

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tic or at least unsettling, so imagine how a child feels. Fear, sadness and anxiety are all symptoms of relocation for children too.

It

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

is critical for parents to make the relocation process as pain free as possible for children. Children must be made to feel included in

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

the relocation and be made fully aware of where they are going. By being part of the relocation a child feels more involved and informed

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

and thus reduces their levels of tension and fear.

Below are some tips for parents on how to help their children enjoy the relocation

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

process:

Explain the relocation – talk the children through the relocation process. Why are we moving? When? How? Will we come back ‘ho

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

me’? Where will they live? What about their friends?

Involve the children – let your children help where they can by looking at brochur

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

es for apartments or houses, potential schools, picking removal companies, packing and arranging a good-bye party for friends and family

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Personal Possessions – if your children are attached to certain things such as a pet, toy, book, clothes or blanket make sure you take

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

them with you. This makes the new home seem more familiar.

Learn about the host country – make an effort to teach the children as much

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

as you can about their new home in imaginative ways. Show them pictures, books, movies, magazines and brochures. If you are moving to I

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ndia take them to an Indian restaurant. If you are moving to the Gulf take them to a mosque. The more they learn about the country the l

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ess they fear the relocation.

Learn the Language – if there is enough time before the move, have your children take language lessons. T

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

his will equip them with a useful skill when they arrive in the new country and make it seem less alien.

Find a pen pal – try and find

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

pen pal for your children from the new country. This will help the children become excited about the move and enable them to learn a li

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ttle about the new culture.

Convey excitement – it is critical that parents always express a sense of excitement, wonder and adventure

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

when discussing the relocation. If the relocation is talked about negatively or hesitantly the children will always pick up on it.

Thes

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e are but a few tips that if followed will help your child come to terms with and positively become involved with the relocation process

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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