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Are you finding spots that just appear out of nowhere on your carpet? Is it driving yo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

u crazy trying to figure out where they came from? If so read this article and learn a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

bout the source of the most common carpet mystery stains.

The most common source of m

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ystery stains is residue from spot cleaners. They appear as dark spots on the carpet t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hat gradually get darker with time. What happens is that you clean a spot with a comme

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rcial spot cleaner and it leaves a great deal of soil attracting residue on the carpet

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

. As people walk on it, dirt is slowly drawn to the spot making it appear dark over ti

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

me. To solve this problem you should try to use spotters only when absolutely necessar

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

y. Try plain water first. You might be surprised what it can clean out. If you must us

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e a spotter use it sparingly and try to rinse it with plain water when you are done.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Another common source of mystery spots is drink spills. This is especially true if you

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

have children who carry around drinks and sippy cups. They spill a clear sticky liqui

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

d which over time attracts soil just like the spotter residue can. To cure this try to

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

keep drinks in the kitchen and clean the spots with plain water or spotter followed b

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

y plain water to remove the residue.

One final source of common mystery spots is acne

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

medication. if you have teenage kids with acne you might be familiar with these spots

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

. Acne medication spilt on the carpet will quickly bleach the carpet leaving light or

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

even white spots on the carpet. There is no cure for these spots except to have a prof

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

essional spot dye them.

These are three of the most common types of mystery spots. Ho

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

pefully you will use this article to fix or prevent them from happening on your carpet

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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