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Mix big screen home theater dreams with a skimpy budget and you have the makings of a fantastic do-it-yourself project. Just think of

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

how impressed all your friends will be watching blockbuster movies on a video projector you made with your own 2 hands.

It was just

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

these motivations that landed me in front of my web browser digging for information for this project. There are a lot of cheesy webs

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ites that promise the moon and sell you a plastic magnifying lense and the instructions to stick a television into a box and put this

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lens on the front. You will get an image, but it will look like you made it yourself. - dark, and blurry.

Is there any way to make

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

this work? The short answer is yes. A video projector is essentially a high resolution LCD video screen with a really bright light sh

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ining through it and a projector lense enlarging onto the screen. New portable models use very tiny, and expensive, LCDs along with

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

sophisticated light sources and high quality lenses. If you are willing to end up with a projector that isn't quite so tiny, you can

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

scavenge the parts you need from an LCD computer monitor and add some electronic components and relatively inexpensive lenses. For $2

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

00-$500 you should be able to create a high resolution bright projector that will really impress your friends.

The parts you

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

need are:

High resolution LCD computer monitor

Projector lens (and possibly 2 fresnel lenses dependin

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

g on the plans you use)

Cooling fan(s) - bright lights get hot when you shove them in a box

Bright lightsource (o

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ne approach to the project is to use an old overhead projector)

Electrical power supply

There are dozens of we

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

bsites with step-by-step plans for free or for sale. Some sell parts that you'll need. Two that I've found to be excellent are Lum

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

enLab and the DIY Projector Company. They both sell parts and parts kits. LumenLab sells a very nicely produced PDF instru

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ction guide with detailed plans. DIY offers plans free, but expects that you'll buy one of their kits to actually make the projector.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

They both use the LCD in a box with a lamp approach.

InventGeek has a great article explaining the whole process in depth including

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

the theory behind projectors. I recommend you check it out. The DenGuru website shows another approach to the project. They use an o

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ld overhead projector for both the lightsource and lens. You strip the LCD panel out of its frame and lay it on the projector like a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

transparency. Ugly, but it works! Check out their tutorial.

Break out your toolkit and get busy - and let's be safe out there people

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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