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Delicious - Polishing Granite
Of all the natural stones that you can choose for flooring granite is by far the hardest material and the most hardwearing. It is also resistant to stai
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ning and acid and alkaline chemicals. This is the reason it is the kitchen worktop of choice and the flooring material of choice.
Despite its hardness
Despite its hardness
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
t is still capable of being scratched by quartz. Quartz is sand like material which makes up the biggest proportion of dirt brought into a building on t
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
e underside of footwear. Traffic going over this then moves the small particles of sand over the surface of the granite causing minute scratches. The s
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
cratching effect on granite will be much less than that on marble for instance but non-the-less it still scratches.
This effect can be minimized by the
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
correct maintenance programme. A typical maintenance programme for granite flooring would be to dust mop the floor each day to remove these particles o
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
dirt and once or twice a week depending upon traffic wash the floor with stone soap. This reseals the floor and enhances the colour. This is then wet v
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
acuumed up and the floor then washed with pure water which is also wet vacuumed up. This wet vacuuming prevents the possibility of water staining.
Once
Once
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
per week or once every other week, again depending upon traffic the floor is misted with a crystallising agent and buffed at high speed. This removes th
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
minute scratches and restores the shine to a floor which may be dulling very slightly in areas of high traffic. Then once per year it can be shined usi
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
g a more abrasive crystallising compound and a slow speed buffer with non-rusting steel wool pads.
If this regime is followed then the shine on the gra
If this regime is followed then the shine on the gra
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
nite floor should last for as long as you require it.
If the floor becomes neglected and is not cleaned correctly then it will slowly become dull and t
If the floor becomes neglected and is not cleaned correctly then it will slowly become dull and t
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
e scratching will build up enhancing the dull effect. If this was a marble floor then the scratching would be greater and could be removed and the shine
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
restored by using diamond grinders on a slow speed buffing machine. However successful re-grinding of granite cannot be achieved. It can be re-ground us
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
ing the diamond technique and made shiny but quite often it causes a colour change in the granite which is obviously not acceptable to the customer.
Th
Th
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
s regrinding process which for marble might take about 30 minutes per square meter for granite, being much harder takes about two to three hours to achi
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ve any sort of shine.
In the processing plants marble is ground for about 40 minutes to achieve the high gloss effect. Granite on the other hand will b
In the processing plants marble is ground for about 40 minutes to achieve the high gloss effect. Granite on the other hand will b
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
e ground for several hours to achieve the same effect. There is no way that once the granite is in place this process can be replicated.
Consequently i
Consequently i
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
you have a granite floor and it dulls and somebody offers to restore the shine by re-grinding it do not bother. You will end up with a floor that may b
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
shiny but has probably changed colour and it will have cost you a small fortune. Take care of it from the outset and you will never be in this position
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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