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In order to decide whether medication is right for you if you suffer from repeated and frequent panic attacks, you will have to discuss with your physician several factors

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

connected with your affliction. Usually, patients and doctors have to consider two main options applicable for any successful treatment.

Prescription medications

The firs

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

t option is medication, of course. A majority of patients suffering from panic disorder are found to be victims of either agoraphobia (literally, fear of open spaces, but a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ctually, a severe anxiety condition in which a person avoids not only open spaces but also situations involving activities like driving, shopping, traveling, being alone or

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

among crowds etc.) or some social phobia (by which is meant fear of failure in some important social interaction or anxiety related to social performance). Others have an

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

anxiety disorder or depression or both, which accompany panic disorder. Depending upon the severity of panic attacks and the symptoms associated with them, the doctor will

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

advise the course of treatment and the type of medication.

The doctor may prescribe either SSRIs (Selective Serotonin Reuptake Inhibitors) or TCAs (Tricyclic Antidepressan

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s) for controlling and reducing the severity of panic attacks. Normally, it may take anywhere between 6 to 12 weeks for the medication will prove effective. After about si

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

x months, the medication may be gradually reduced and stopped, while carefully monitoring the patient’s withdrawal symptoms and relapse possibilities. The actual duration o

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

f the medical treatment will depend naturally on the individual’s speed of response to it. The specific medication selected for use by a certain patient has to have the pat

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ient’s acceptance, after clearly being told about the various side effects of the chosen antidepressant.

Cognitive Behavior Therapy

The other option may be put under the

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

term CBT (Cognitive Behavior Therapy). Although many doctors would like to recommend a treatment that allows medication to be administered along with CBT, if you do not lik

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e to suffer the side effects of medication comprising antidepressants, you may opt to undergo CBT alone. In that case, you have to be aware that the reliability of CBT with

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

out the use of any medication is quite limited. Besides, it is quite a long-drawn process, which may sometimes take several years to be really effective. This is because th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

patient takes time in identifying the feelings that, due to their misinterpretation, form the basis for panic attacks. The patient also has to have time enough to be prope

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

rly educated about panic attacks and their prevention. This means it is imperative for the patient to understand and appreciate the nature of panic attacks and how to face

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

the various symptoms without succumbing to their severity. This is just the cognitive part of the therapy.

The other part of CBT comprises bringing about behavioral change

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s. The patient has to learn proper breathing so as to prevent hyperventilation, which is a very common symptom of a panic attack. The patient has also to learn relaxation t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

echniques that help calm the nerves. Meditation may be useful for relaxation and mental health. Physical exercise done on a regular basis will also be good. Bringing about

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

suitable lifestyle changes is usually recommended.

You must decide in consultation with your doctor and other health care professionals whether medication is right for you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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