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I thought I would draw this article up as a reference page in the event any of you would ever need, at a quick glance, exactly what the 10 commandments are. Most Christians do not have all of them memorized.

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

I will actually type out the specific Bible verse the 10 commandments comes off of as God makes some additional statements under some of these commandments that is usually not written down when you see little

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tablets of the 10 commandments at your local Christian bookstore.

Before I type out the verse, consider one thing. Even though the 10 Commandments are from the Old Testament, these commandments still apply

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

for everyone today. No exceptions! I call each of these commands "stone commandments."

The fact that God would manifest 10 specific commandments on a tablet of stone tells me that He is deadly seri

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ous about these specific commandments! This was one big huge event when it happened in the story of Moses. The fact that God would go this far in manifesting these special 10 commandments tells me that th

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ese commandments should not be taken lightly or for granted.

Most Christians have heard all about these 10 commandments while going through grade school and high school and the story as to how they came abou

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t. As a result, I feel that many Christians take these 10 for granted and really do not realize the power and authority that is on these special 10.

The 10 commandments come from Exodus 20:1-17. Here is the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

verse: And God spoke all these words, saying: "I am the Lord your God, who brought you out of the land of Egypt, out of the house of bondage.

You shall have no other Gods before me.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

You shall not make for yourself any carved image, or any likeness of anything that is in heaven above, or that is in the earth beneath, or that is in the water under the earth; you shall not bow down to them

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nor serve them. For I, the Lord your God, am a jealous God, visiting the iniquity of the fathers on the children to the third and fourth generations of those who hate me, but showing mercy to thousands, to th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

se who love Me and keep My commandments.

You shall not take the name of the Lord your God in vain, for the Lord will not hold him guiltless who takes His name in vain.

Remember the Sab

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

bath day, to keep it holy. Six days you shall labor and do all your work, but the seventh day is the Sabbath of the Lord your God. In it you shall do no work: you, nor your son, nor your daughter nor your man

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

servant, nor your cattle, nor your stranger who is within your gates. For in six days the Lord made the heavens and the earth, the sea, and all that is in them, and rested the seventh day. Therefore th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e Lord blessed the Sabbath day and hallowed it.

Honor your father and mother, that your days may be long upon the land which the Lord your God is giving you.

You shall not murder.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

You shall not commit adultery.

You shall not steal.

You shall not bear false witness against your neighbor.

You shall not covet your neighbor’s house; you shall not

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

covet your neighbor’s wife, nor his manservant, nor his maidservant, nor his ox, nor his donkey, nor anything that is your neighbor’s."

The above commandments need no explanation. They mean e

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

xactly what they are saying. It’s quite amazing how many of these commandments are being broken on a regular basis even by Christians themselves. If you look closely at each of these commandments, they really

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

do cover a broad spectrum as to what God is expecting from each one of us.

They are good, basic laws that will keep us right before God and keep us out of trouble with ourselves, our families and our neighb

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ors. God knows what is best for us and our families, and He wants all of us to stay out of trouble in order that we may live in peace with Him and one another.

The fact that God would go so far as to have th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ese 10 basic commandments manifested on a stone tablet really tells me that they are very important and that each Christian should know what they are and do their best to abide by them

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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