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    Paul is led up a 512 ft. hill, Mars Hill, also known as Areopagus, and there he faces the Epicureans and the Stoics (and others). These intellectual giants represented the philosophical thinking of the day in which Paul lived. And when these PhD’s saw Paul, they sneered and considered him a vain babbler (
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    seed picker). They had given Paul audience merely to amuse themselves by listening to what he had to say.

    Now, the Stoic religion, founded by Zeno (c. 300 B.C.), was rooted in the art of living wisely. Their teaching suggested that the ultimate principle of the universe and the ideal of the ethical life
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    s to live in harmony with reason. Reason will keep each man under control. God was thought to be the indwelling reason, the soul of the universe and apart from it, God had no existence. So according to stoicism, the fundamental injunction laid upon man was to follow the law of nature and maintain self dis
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    cipline by listening to the voice of reason.

    I think the Stoics made a good point because if we investigated the doctrines and practices of most of the major religions, we will find something comparable to the teachings of Christianity. We can look at Buddhism or Confucianism or Hinduism and find teachin
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    s against murder, stealing, adultery and so forth. And so the Stoics believed there was something in our natural thinking process that would lead us to do the right thing. Paul contemplated this philosophical leaning and came up with a gospel that seemed to undercut what the Stoics believed. I imagine Pau
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    l saying something to the effect: Men of Athens,
    I can appreciate your philosophical thought that there is something in the laws of nature that will lead us to do the right thing. I understand what you are saying concerning the laws of nature, but I do not think you have considered huma
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    nature. You see, just because we know what is right does not mean we will do what is right. Just because we know we should not lie does not mean we will not lie. Just because we know we should not gossip on each other, stab each other in the back, dig ditches for one another, does no
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    t mean we will not do it. But my gospel takes into account human nature. Because I discovered the other day that even when I would do right, even when reason does lead me to do the right thing, evil is always present.

    As intelligent as we may consider ourselves, we cannot afford to rely
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    solely on reason. When we have done all the thinking we can do, we will realize that there are some things beyond reason. We know this because if we stop to think about it, we would have to admit that the virgin birth is not logical. The turning of water into wine is not logical. It is not reasonable to a
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ccept the idea of a man walking on water. But the gospel transcends logic. The doctrine of the gospel is a great mystery of godliness. It is out of the road of the enquiries of human reason; it transcends the finiteness and limitations of man.

    The Epicureans were also on Mars Hill. They believed in the a
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    t of living happily. They considered pleasure of mind and body to be the highest good in life. Life to the Epicurean is simple fulfillment of natural desires which they felt rendered a life of security and lasting pleasure. They emphasized and sought to maximize the happiness of the majority and did not w
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    rry about the rest. For them, the chief end of man was to eat, drink and be merry.

    Well, I can hear Paul telling the Epicureans,
    There is nothing wrong with wanting to be happy. It is great to want to maximize the happiness of the greatest number, but my gospel also considers the few.
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    There may be a few folks out there who cannot afford the cost of an education. There may be a few folks out there who are struggling trying to make ends meet. There may be a few folks out there who are not listed among the fittest; because under the evolutionary program, only the fittest will survive. If
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ou are not fit, you’ll be lost. But under the Gospel that I represent, it does not matter who you are, God cares.

    Unlike man, God's love is not conditional and not predicated on who you are, where you are, where you live or your education. You can be the President of the United States o
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    r you can be a sanitation worker for the city, God cares for you. It doe not matter where you are – you can be on top of the mountains or you can be on the bottom of the barrel, God still cares. It does not matter what street you live on. You can live in the richest neighborhoods or you can live in the gh
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ttos of America, God still cares. Maybe you do not have a degree behind your name, maybe you do not know how to make the subject and the verb agree; God still cares for you.

    Paul looked at the surroundings he was in and could hardly believe what his eyes were seeing. Athens was famous for their temples t
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    hat were exquisite works of art. There was no other place on earth at the time where so many idols were exhibited. It was often said that it was easier to find a god than a man in Athens. Paul observed the many temples, surrounded by statutes of deities and gods of many natures. There were thousands of pu
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    lic statutes and thousands more in the Parthenon. Athens was not only the home of the great philosophical thinkers; it was the home of the Greek gods of mythology. Many deities were housed in the temples and shrines of men's hearts and minds including Zeus, Apollo, and Narcissus. So Paul challenged them w
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ith the preposterousness of all the idols. What he said to them was tantamount to:

    I’ve noticed you have a lot of idols up here. Everywhere I look, I see idols. I have even noticed an altar with the inscription – To the Unknown God. Here you sit like you have all the answers, like you ha
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    e a monopoly on wisdom and yet the true God is an unknown God. Well, let me tell you about this unknown God.

    The Good News from Mars (Hill) is that God cares. He cares for you in a personal and intimate way. It does not matter who you are, where you are, what your circumstance, God cares


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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