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    Throughout the ages mankind has attempted to control his world around him by many different means. In the physical world we have invented all kinds of
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ways to make our lives better. If you believe the bible then in the beginning everything was perfect, mankind was in need of nothing. God took care of
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    everything, He provided food and not much else because there was no need for much else. Mankind did not even need clothes. Can you imagine that, everyb
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    dy going around totally naked! Anyway if we are to believe the bible, and I do by the way , I am a Christian, mankind began to look out for themselves
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    after the story of thru fist sin. The first item they made was clothes. Thereafter we have been constantly inventing and making anything that will make
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    life easier for ourselves, from houses to cars, boats, airplanes, microwave etc, etc. Look around you, with every glance of the eye you will see someth
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ing that mankind has made in an attempt to better out lives. That is unless you are in the middle of some untouched part of the world where man has yet
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    to disturb and even then you are probably not naked. We must admit that as far as material things go we have come a long way. The question is, with all
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    that we have done materially to make life better, why is it that so many people are unhappy, feel that they are not loved, many do not see any purpose
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    in life and tragically some reach the point of ending it all in suicide. This is the question, why?

    There must be another aspect, another dimension to
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    our lives that we need to be mindful of. This other realm is the spiritual, or the supernatural or whatever you want to call it, the realm of the mind
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    . More and more we are beginning to realize that this world, this spiritual world, is what really controls us and all that we do is a result of what’s
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    oing on in the mind. The wisdom literature of the ages all point to this fact that it is not what you have on the outside that really matters, but what
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    you have on the inside.

    Eastern religions do meditation and things like yoga exercises all intended to improve your state of mind. Christians believe
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    in a life changing power coming from God that manifests itself from the inside out through prayer and meditation and a study of the bible. We can see t
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    hat all of these religions seek to bring about change in our lives by changing our thoughts, what goes on in our minds. Quite recently I have come upon
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    what is a new subject to me and that is the power of manifesting. This is where one zeroes in on our thought processes and literally attempts to bring
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    about something, be it a physical item or an intangible such as wisdom for example, by using the power of our minds. Christians would call it a prayer
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    f faith, where they believe for something and that God would bring it to pass. It is a very interesting topic and one in which we might all benefit if
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    we can approach this it with an open mind. No matter your religion, or your prior spiritual beliefs there may be something in manifesting for all of us


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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