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Do you believe that drinking lots of water will help you lose weight? This is a m

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

yth. Drinking extra water with meals will not reduce the amount of food that you

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

at. If you drink several glasses of water with your meals, the extra water will di

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

stend your stomach and make you feel full for a minute or two, but the water leave

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

your stomach so quickly that you feel hungry again. The only stimulus to make you

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

stop eating is to take in enough food to make you feel full and satisfied. Water h

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

as no calories and does not satisfy hunger.

Most of your requirements for water a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e met by the food that you eat. A normal day's food contains about 4 cups of water

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

. The chemical reactions that occur as you burn calories add another 2 cups of wat

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

r, for a total of 6 cups. You can easily meet your need for additional water each

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ay just by drinking a couple of glasses of water or any other liquid.

Healthy kid

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

neys are so effective in clearing extra fluid from your body that healthy people c

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n take in extra water safely. Your kidneys can clear 5 gallons of water per day or

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

a half glass of water every 15 minutes. If you exceed your upper limit for water,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

you may develop a headache, nausea and even seizures. However, drinking extra wate

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

contributes nothing to your weight loss efforts.

Foods that are high in fiber an

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d water content help you lose weight because they fill you up without a lot of cal

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ries. They take a long time to digest, so the added volume from water bound up wi

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

th fiber keeps you feeling full and you eat fewer total calories. Forget about dr

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nking extra water; instead, eat lots of fruits, vegetables, whole grains and beans

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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