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Onions don't just make us cry and garlic isn't just for vampires. Onions and garlic have been used as spices in cooking for thousands of years and they are usually the first ones

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

thrown in to the frying pan. However, these tasty ingredients are often confined to the kitchen because few people know of the many uses of garlic and onions outside cooking. The

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

y contribute a lot to our health and are a couple of the more widely used herbs in alternative medicine.

Onion

From the early beginnings of traditional medicine, the onion has be

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

en famous for its healing powers. Onions were speculated to have antiseptic properties and were often used in wound dressings and washes to protect wounds from infection. When t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ken internally, as in onion soup, it is an effective expectorant for coughs, colds and even bronchitis. Slow and frequent sips of the soup were thought to relieve sore throats and

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

sinusitis. It could also break high fevers.

Onions are thought to have diuretic properties and are good for people suffering from arthritis and gout. Onions were used as a reme

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

dy for flatulence and constipation as well as disorders of the liver. It is also considered generally as an aid in digestion by acting as a tonic to the liver thus stimulating it

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

to produce bile.

Onions are famous for their ability to lower high blood pressure and dissolve and prevent the formation of blood clots by improving circulation. It also purifies

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the blood with its diuretic property. Cases of anemia have also been treated with onions.

When used externally, onions can remedy a lot of skin problems. The juice of the onion

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

is widely used in the treatment for stings, insect bites, animal bites, cuts, boils, abscesses and even burns. Onion juice is also good for toothache, earache and warts. A poulti

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ce made of onions is known to cure chilblains. When inhaled, it can relieve headaches. Lastly, when handled correctly, onions can be a very potent aphrodisiac.

Garlic

Nowadays,

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

garlic is mostly thought of as a culinary component. But with the recent emergence of garlic pills that are used as a health supplement for certain conditions, people are startin

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

to realize its healing prowess. As with the onion, the use of the bulb of the garlic in herbal medicine dates back at least a thousand years and it is used in a lot of different

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ways. Garlic is known for its ability to prevent and cure infections. It is also well-known in treating simple to serious respiratory disorders such as asthma, influenza and sore

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

throats, bronchitis and lung infections. Garlic is also used as a decongestant and expectorant to relieve the discomforts of asthma, cough and chest infections.

In the digestive

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

system, garlic has been found to have a good effect on the liver and also in the intestines for it helps flush out worm infestations. It is a general cleanser of the alimentary c

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nal and an over-all aid to digestion.

Probably the most profound of its benefits is its ability to treat certain disorders of the blood. It has the ability to lower blood pressur

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e as well as blood sugar levels. It can also treat excessive blood clotting.

When used externally, it also has a lot of benefits. Garlic is crushed and macerated then mixed with

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

oil or made into an ointment. This is effective in treating stings, insect and animal bites, cuts and ringworm. This mixture or ointment applied to certain areas is able to reli

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

eve the pain and inflammation of the joints in rheumatism and sprains. When rubbed into the chest, it could also lessen labored breathing and chest infections as well as earaches

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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