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There is something about women and their uncanny knack to remember important dates. A woman almost never fo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rget dates even if they are as insignificant as the birthdays of their boyfriends' parents but when it come

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

to men, they become geeks, if they remember significant dates. However there surely are some who feel that

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

special dates ought to be remembered.

Let's explore how important it is to remember important dates, while

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

in love...

Significant dates are pivotal. For most people remembering special dates is yet another express

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

on of love. Not only does it help to make each other feel special, but also cements the bond of love that y

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ou share. "My boyfriend and I always celebrate the 25th of every month with great zeal and spirit, because

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t was on that date in January that we both met. It's special and we always reminisce on how we fell so deep

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

y in love. Invariably there is also a present waiting for me. Not only the 25th of every month, we try and

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

emember important birthdays of his and my family members. It's just another way of reinforcing that you car

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

," says Andrea Scott, a consultant.

For many, a sharp memory that retains important dates can also be a bl

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

essing in disguise. "Last year I very conveniently forgot my mom's birthday but somehow my husband remember

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

d and thank God for it. Because I would have felt eternally guilty had it not been for his ability to remem

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

er dates. I guess it's a part and parcel of being in love that you remember your partner's family members'

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

irthdays," says Ronit Jones, a doctor.

So, how and why do dates matter when you are together? For many peo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

le, dates have absolutely no significance. The day you met the love of your life was just another day in th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e calendar. "It has always intrigued me why my wife threw big fits when I forgot our anniversary and even h

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r birthday. It took me such an effort to remember those dates amidst my hectic schedule. Sometimes even the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

alarms would fail to go off on time and there I would be, in the middle of a huge storm at home. I guess it

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

adds to life's pressure - remembering dates. Why can't life be simpler?" says Roger Benjamin, a businessman

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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